TWiP 266: Wraps and ivermectin for malaria

TWiP explains research showing that treatment of baby wraps with an insect repellent, and oral dosing with ivermectin, are both effective measures to...

TWiP 265: Things that jump are cleaner than things that squat

TWiP solves the case about the parasite check in summer camp, and presents a new case about a woman who traveled to Brazil and developed furuncles on...

TWiP 264: Toxoplasma changes your brain

Vincent and Daniel discuss research showing that Toxoplasma gondii infection of the brain alters extracellular vesicle production and the communicatio...

TWiP 263: Tick-tock

TWiP solves the case of the world travelers with poppy-seed size dots embedded in their skin, then present a new case about parasite check in summer c...

TWiP 262: Do schistosomes affect behavior?

TWiP reviews research suggesting that schistosome infection affect behavior through the gut-brain axis, and Chuck Knirsch joins to reminisce about Dic...

TWiP 261: A case for Dr. Hickam

TWiP solves the case of the pregnant woman from Tanzania with dehydration and 3 weeks of bloody stool, a situation that would confuse Ockam but not Dr...

TWiP 260: Daily rhythms

TWiP explains how circadian clocks of parasite and vector circadian mediate efficient malaria transmission.
Subscribe (free): Apple Podcasts, Go...

TWiP 259: Know your knowlesi

TWiP solves the case of the man in the Malaysian city of Kucheng who presents with daily fevers and shaking chills, and serve a new clinical puzzle fo...

TWiP 258: The deeper, the rounder

TWiP describes how a gut commensal protozoan influences respiratory disease outcomes by shaping pulmonary immunity, and body shape variation in lice t...

TWiP 257: Malaya and Malaysia

TWiP solves the case of the man in the Malaysian city of Kucheng who presents with left arm swelling, and presents a new case for you to decipher.

TWiP 256: Amazing antimalarial drug resistance

TWiP explains a study that carries out selection of Plasmodium falciparum in the presence of inhibitors to identify determinants of drug resistance, a...

TWiP 255: Katayama fever

Michelle Labrunda joins TWiP to solve the case of the Georgian in Guinea with fever and dry cough, and describe a new case for you to solve.
Hos...

TWiP 254: Our hero Dickson

TWiP explains a study which finds that tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei, then remembers our departed colleag...

TWiP 253: Sub-Saharan somnolence

TWiP solves the case of the man with somnolence and something extra-erythrocytic, and presents a new puzzle for you to solve.
Hosts: Vincent Rac...

TWiP 252: For malaria vaccine, mosquito is the needle

TWiP discusses a study of the safety and immunogenicity of a late liver-stage attenuated malaria parasite delivered by mosquito bite.
Hosts: Vin...

TWiP 251: Case of the facial ulcer

TWiP solves the case of the woman who went to Belize and notices a lesion on her face, and presents a new clinical case for you to solve.
Hosts:...

TWiP 250: Gut bacteria help Trichinella suppress colitis

TWiP reviews a study showing that the gut microbiota is essential for suppression of colitis by Trichinella spiralis.
Hosts: Vincent Racaniello,...

TWiP 249: A virus and a parasite

TWiP solves the case of the middle-aged man with eosinophilia and a history of sexual activity with paid sex workers in Okinawa, and presents a new ca...

TWiP 248: Toxoplasma reduces Alzheimer's disease

TWiP reviews the observation that infection of Azlheimer’s disease mice with Toxoplasma gondii reduces brain amyloid density globally and regionally.<...

TWiP 247: Manhattan mystery malady

TWiP solves the case of the Manhattan man with pain on urination or ejaculation, and presents a new case for you to solve.
Hosts: Vincent Racani...

TWiP 246: Everything spiral: a worm in a hurry

TWiP taps into Dickson’s knowledge of Trichinella to discuss an outbreak in humans who consumed rare bear meat, and the impact of globalization and cl...

TWiP 245: Flying purple people eater with Ben LaBrot

Founder of Floating Doctors Ben LaBrot joins TWiP to solve the case of the 1 year old in northeastern Panama with a fatal leg infection, followed by a...

TWiP 244: Engineering Toxoplasma

Lilach Sheiner joins TWiP to talk about her career and her work on engineering Toxoplasma gondii secretion systems for intracellular delivery of multi...

TWiP 243: Don't blame it on Mexico

TWiP solves the case of the Woman with White Worms, and submits a new case involving a 1 year old in northeastern Panama with a fatal leg infection.

TWiP 242: Worms impair COVID vaccines

TWiP reviews a study showing that intestinal helminth infection impairs vaccine-induced T cell responses through an IL-10 pathway, which compromised p...

TWiP 241: There once was a patient from China

TWiP 240: A daily history of malaria with Sean Murphy

Sean Murphy joins TWiP to discuss his career and the work of his laboratory to assess the daily natural history of asymptomatic Plasmodium infections...

TWiP 239: Cryptosporidiosis from NYC tap water in an AIDS patient

TWiP solves the case of the AIDS patient who developed fever and watery diarrhea after drinking NYC tap water, and present a new case for your sleuthi...

TWiP 238: Eliminating sleeping sickness

Michael Barrett joins TWiP to discuss progress in the elimination of human African trypanosomiasis caused by Trypanosoma brucei gambiense.
Hosts...

TWiP 237: Pass the venison, deer with Marilyn Fabbri

Marilyn Fabbri joins TWiP to reveal the case of a patient who became very ill after he and a number of friends attended a large dinner where venison a...

TWiP 236: Prime-and-trap vaccine for malaria

Marion Avril of MalarVx, Inc. joins TWiP to discuss an accelerated prime-and-trap regimen using repRNA-based circumsporozoite vaccine.
Hosts: Di...

TWiP 235: The case of the regurgitated wriggler

TWiP solves the case of a man in his 50s reporting months of abdominal discomfort, who takes mebendazole and some time afterwards vomits a worm into t...

TWiP 234: Hookworms and a leech - parasites suck!

TWiP discusses hookworm infection and the phase 1 clinical trial for a hookworm vaccine that could one day protect children from the hookworm anaemia,...

TWiP 233: Cryptosporidium not cryptocurrency

TWiP solves the case of the physician with no significant previous medical history who is currently doing their fellowship training develops diarrhea,...

TWiP 232: Lives of Wolbachia

TWiP reviews the cellular lives of Wolbachia, a gram-negative bacteria that infects many arthropods and filarial nematodes with very different outcome...

TWiP 231: Scotch in drink and tape

TWiP solves the case of the Woman With White Worms, and presents a new clinical case to decipher.
Hosts: Vincent Racaniello, Dickson Despommier,...

TWiP 230: Healing cutaneous leishmaniasis with Maria Adelaida Gomez

Maria Adelaida Gomez joins TWiP to discuss her career and the work of her laboratory on understanding the healing process during cutaneous leishmanias...

TWiP 229: The very hungry flatworm

Eyal joins TWiP to solve the case of the Female Traveler with Intermittent Fever and Ring Enhancements in the Liver.
Hosts: Vincent Racaniello, ...

TWiP 228: Parasitic fountain of youth

TWiP discusses a tapeworm that causes extreme lifespan extension in infected ant workers, and a candidate antibody drug for prevention of malaria.

TWiP 227: Alpha-gal syndrome

Jim Small joins TWiP to solve the case of the 41 year old Man with sudden GI distress and itchy hives, followed by a discussion of parasites and child...